GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7104764 | 1 | rs6598065 | chr11:243211 | PSMD13 | chr11:236808-252984:+ | -0.22 | -6.72 | 5.21E-11 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598065 | chr11:243211 | SIRT3 | chr11:214625-236931:- | 0.12 | 3.41 | 0.000702 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598066 | chr11:243185 | PSMD13 | chr11:236808-252984:+ | -0.22 | -6.67 | 7.15E-11 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598066 | chr11:243185 | SIRT3 | chr11:214625-236931:- | 0.12 | 3.49 | 0.000534 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598069 | chr11:240664 | PSMD13 | chr11:236808-252984:+ | -0.22 | -6.75 | 4.25E-11 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598069 | chr11:240664 | SIRT3 | chr11:214625-236931:- | 0.12 | 3.38 | 0.000785 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598074 | chr11:219398 | PSMD13 | chr11:236808-252984:+ | -0.21 | -6.41 | 3.55E-10 | Menarche (age at onset) |
| THCA | cis | rs7104764 | 1 | rs6598074 | chr11:219398 | SIRT3 | chr11:214625-236931:- | 0.12 | 3.54 | 0.000435 | Menarche (age at onset) |
| THCA | cis | rs6598955 | 1 | rs6598955 | chr1:26619649 | CNKSR1 | chr1:26503981-26516373:+ | -0.15 | -4.23 | 2.86E-5 | Obesity-related traits |
| THCA | cis | rs6598955 | 1 | rs6598955 | chr1:26619649 | ZNF593 | chr1:26496388-26497362:+ | 0.14 | 4.22 | 2.98E-5 | Obesity-related traits |
| THCA | cis | rs9815354 | 1 | rs6599170 | chr3:41772718 | ULK4 | chr3:41288091-42003660:- | 1.05 | 19.38 | 3.47E-62 | Diastolic blood pressure |
| THCA | cis | rs9815354 | 1 | rs6599175 | chr3:41786009 | ULK4 | chr3:41288091-42003660:- | -1.07 | -19.74 | 7.34E-64 | Diastolic blood pressure |
| THCA | cis | rs9815354 | 1 | rs6599176 | chr3:41788492 | ULK4 | chr3:41288091-42003660:- | -1.04 | -19.1 | 7.92E-61 | Diastolic blood pressure |
| THCA | cis | rs9815354 | 1 | rs6599178 | chr3:41842129 | ULK4 | chr3:41288091-42003660:- | 1.09 | 20.79 | 7.26E-69 | Diastolic blood pressure |
| THCA | cis | rs9815354 | 1 | rs6599179 | chr3:41855284 | ULK4 | chr3:41288091-42003660:- | 1.09 | 21.2 | 8.24E-71 | Diastolic blood pressure |